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Caring for the Critically Ill Patient

Explore JAMA’s influential critical care medicine series, including new guidelines, important clinical trials, and more on topics such as sepsis and respiratory failure and ventilation.

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JAMA

Medical News & Perspectives

Using “Power Prescriptions” to Counter Energy Insecurity

Anika Nayak

Original Investigation

Dapagliflozin in Critically Ill Patients With Acute Organ Dysfunction

Caio A. M. Tavares, MD, PhD, Luciano C. P. Azevedo, MD, PhD et al.

Editorial

SGL-2 Therapy for Acute Organ Dysfunction

Hernando Gómez, MD, MPH, Lennie P. G. Derde, MD, PhD

Review

Low-Dose Corticosteroids for Adults With Severe Pulmonary Infections

Romain Pirracchio, MD, MPH, PhD, Balasubramanian Venkatesh, MD et al.

Original Investigation

Prolonged vs Intermittent Infusions of β-Lactam Antibiotics in Adults With Sepsis or Septic Shock

Mohd H. Abdul-Aziz, BPharm, PhD, Naomi E. Hammond, RN, PhD et al.

Original Investigation

Continuous vs Intermittent β-Lactam Antibiotic Infusions in Critically Ill Patients With Sepsis

Joel M. Dulhunty, MD, PhD, Stephen J. Brett, MD et al.

Editorial

Resolving the Dilemma on Continuous vs Intermittent β-Lactam Antibiotics in Sepsis

W. Joost Wiersinga, MD, PhD, MBA, Michiel A. van Agtmael, MD, PhD

Viewpoint

Failure to Rescue as a Quality Measure in Sepsis

Stephanie Parks Taylor, MD, MS, Marc Kowalkowski, PhD

A Piece of My Mind

The Other Side of the Curtain

Paige Stevens, MD

Original Investigation

Acetaminophen for Prevention and Treatment of Organ Dysfunction

Lorraine B. Ware, MD, D. Clark Files, MD et al.

Original Investigation

Stewardship Prompts to Improve Antibiotic Selection for Pneumonia

Shruti K. Gohil, MD, MPH, Edward Septimus, MD et al.

A Piece of My Mind

Good Enough

Lauren Rissman, MD

Research Letter

Cardiac Function Before Sepsis and Clinical Outcomes

Stuthi Iyer, MPH, Jason N. Kennedy, MS et al.

JAMA Guide to Statistics and Methods

Effect Scores to Characterize Heterogeneity of Treatment Effects

Guanbo Wang, PhD, Patrick J. Heagerty, PhD et al.

Editorial

Oxygen Supplementation in COVID-19—How Much Is Enough?

Richard M. Schwartzstein, MD

Editorial

Personalized Oxygen Supplementation

Derek C. Angus, MD, MPH

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JAMA NETWORK

Original Investigation

Barriers and Opportunities for Adapting Critical Care Clinical Trials in the Pandemic

Deborah Cook, MD, MSc, Shipra Taneja, BSc, MSc et al.

JAMA Network Open |

Original Investigation

Termination of Resuscitation Rules and Survival in Out-of-Hospital Cardiac Arrest

Michael A. Smyth, PhD, Imogen Gunson, MSc et al.

JAMA Network Open |

Invited Commentary

Optimizing the Value of β-Lactam Antibiotics Through Extended Infusion

Miranda So, PharmD, MPH

JAMA Network Open |

Original Investigation

Outcomes Among Hospitalized Adults Receiving Extended-Infusion β-Lactam Therapy

Sara M. Karaba, MD, PhD, MHS, Sara E. Cosgrove, MD, MS et al.

JAMA Network Open |

Original Investigation

Factors Associated With Quality of Dying and Death Among Critically Ill Patients

Fur-Hsing Wen, PhD, Wen-Chi Chou, MD et al.

JAMA Network Open |

Original Investigation

Empiric Broad-Spectrum Antibiotic Use for Suspected Community-Onset Sepsis in US Hospitals

Chanu Rhee, MD, MPH, Tom Chen, PhD et al.

JAMA Network Open |

Original Investigation

Early Antibiotic Exposure and BPD in Very Preterm Infants at Low Risk of EOS

Wei Shi, MD, PhD, Zheng Chen, MD, PhD et al.

JAMA Network Open |

Original Investigation

Hospital-Onset Bacteremia Among Neonatal Intensive Care Unit Patients

Erica C. Prochaska, MD, Shaoming Xiao, MSPH et al.

JAMA Pediatrics |

Original Investigation

Intravenous Opioid Administration With Mechanical Ventilation and Use After Discharge

Laura C. Myers, MD, MPH, Lauren Soltesz, MS et al.

JAMA Network Open |

Original Investigation

Pediatric RSV Hospitalizations and Respiratory Support After the COVID-19 Pandemic

Zachary A. Winthrop, MD, Jennifer M. Perez, MD et al.

JAMA Network Open |

Original Investigation

Pediatric Respiratory Syncytial Virus Hospitalizations in 2017-2023

Tiffany Fitzpatrick, PhD, MPH, Sarah A. Buchan, PhD, MSc et al.

JAMA Network Open |

Research Letter

Phoenix Sepsis Score and Risk of Attributable Mortality in Children With Cancer

Joshua Wolf, MD, PhD, Zachary Rubnitz, MD et al.

JAMA Network Open |

Original Investigation

Large Language Model Capabilities in Perioperative Risk Prediction

Philip Chung, MD, MS, Christine T. Fong, MS et al.

JAMA Surgery |

Invited Commentary

The Quest for Evidence on Time to Antibiotics in Children With Sepsis

Nora Luethi, MD, Luregn J. Schlapbach, MD, PhD et al.

JAMA Network Open |

Original Investigation

Delays to Antibiotics in the ED and Risk of Mortality in Children With Sepsis

Roni D. Lane, MD, Troy Richardson, PhD et al.

JAMA Network Open |

Original Investigation

In-Hospital vs 30-Day Sepsis Mortality at US Safety-Net and Non–Safety-Net Hospitals

Anica C. Law, MD, MS, Nicholas A. Bosch, MD, MSc et al.

JAMA Network Open |
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